Endocrine Abstracts

Introduction: Serum calcitonin levels (sCT) in medullary thyroid carcinoma (MTC) correlate with the tumour size and disease progression. Lymph node (LN) metastases can be verified even in sCT lower than 100 pg/ml. The extent of LN dissection has not yet been standardised. The aim of this pilot study was to show our experience with sentinel lymph node (SLN) biopsy of jugulo-carotid chain (JCC) in selection of patients with MTC for modified radical neck dissection (MRND).<p ...

Introduction: The aim of this study was to determine frequency of lymphonodal metastases in jugulo-carotid chain (JCC) and central neck compartment in incidental thyroid microcarcinomas (ITMC), as well as to examine whether sentinel lymph node (SLN) biopsy of JCC is an accurate technique to select patients with true positive, but clinically and ultrasonically negative lymph nodes, for modified radical neck dissection (MRND).Materials and methods: Out of ...

Introduction: Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy (80%), while primary thyroid lymphomas (PTL) occur in only 0.6–5% of cases. A significant number of PTCs, as well as PTLs, arise in the setting of Hashimoto’s thyroiditis (HT), however the simultaneous occurrence of these two malignancies is extremely rare.Case report: We present a 34-year-old female patient with thyroid MALT lymphoma and coexisting papillary ...

Introduction: The aim of this study was to determine whether sentinel lymph node (SLN) biopsy of jugulo-carotid chain (JCC) in thyroid microcarcinomas (TMC) is an accurate technique to select patients with true positive, but clinically and ultrasonically N0 LNs, for modified radical neck dissection (MRND).Materials and methods: In total 199 patients with TMC underwent total thyroidectomy, central neck dissection and SLN mapping with 0.2 ml of 1% methylen...

Background: Papillary thyroid carcinoma in children and adolescents is rare but it shows aggressive behavior. Gross lymph node metastases and distant metastases are common on first clinical presentation.Patients and methods: Forty-eight children and adolescents were operated due to PTC. Mean age was 16.6 years (range 7–21). At the time of diagnosis 13% had lung metastases. Total thyroidectomy or completion of thyroidectomy was performed in all cases...

Introduction: The incidence of occult lymph node metastases (LNM) in papillary thyroid carcinoma (PTC) reaches 80%, still their surgical management in clinically node negative (cN0) patients remains controversial and ranges from ‘wait and see’ principle to prophylactic dissections of both central and lateral neck compartments. This encouraged some authors to apply the concept of sentinel lymph node biopsy (SLNb) in PTC. Our aim to investigate if SLNb using methylene ...

Background: The accuracy of sentinel lymph node biopsy (SLNB) in decisions for surgical management of lymph nodes in thyroid carcinoma (TC) was demonstrated in a few previous studies. SLNB was started in good selected cases of medullary TC (MTC) and it is a promising method. Its application to avoid prophylactic neck dissectionAim: To determine whether SLNB of first draining node/s in jugulo-carotid chain is accurate technique to select patients with tru...